A rapist terrorizes the hospital and causes the nurses to refuse to work night shifts. Also, Ben clashes with the medical director, and welcomes Dr. Raleigh Stewart, the new plastic surgeon, and a new psychiatrist.

Ellis works overtime to prepare for her father's impending visit, causing her to grow cranky to the point of mistreating an obese patient. A circus clown attempts suicide. Peeler unwittingly gives damaging testimony against Ben; and Grace breaks up with Weiss.

Ben's mentor, Dr. Langston Ellis, visits the hospital and quickly causes problems with his condescending attitude. The rapist terrorizing the hospital strikes again; and a gunshot groom refuses surgery until he is married to his bride, who is about to give birth to their baby.

Nurses threaten to walk off the job unless a rapist is caught. Ben suggests Ambrose step aside during a complicated surgery. Gewn is confronted by the brother who once raped her; and Damon is furious after being demoted by Ben for trying to cover up a near-fatal mistake.

After Ambrose botches an operation, Ben and Stewart go behind his back and perform the correct surgery, which leads Ambrose to discipline them both. A patient keeps eating people's possessions. Ellis's misdiagnosis nearly costs a boy his life; and Chanley receives some disturbing news.

Dr. Chanley is an emotional wreck after she performs a life-altering operation on the wrong patient and then informs Ambrose that she's pregnant with his child, which he doesn't want. Meanwhile, Syphax and Jackson are rudely received when they drive the hospital's new mobile diagnostic vehicle into a rough neighborhood.

Ben is asked by a terminally ill teen to not perform a scheduled operation on him, even though his parents want it done. Williams orders a Thanksgiving turkey from a questionable source and is surprised at how fresh it really is. An elderly woman, who claims she can sense when death is appraching a person, causes Stewart and Ellis to rethink a patient's diagnosis.

A 12-year-old Somalian girl bleeding from a ritual circumcision is brought in by her older sister. A kidney becomes available to transplant but the patient can't be found. A husband isn't sure if he wants his wife to get reconstructive surgery that will make her beautiful; and Ben receives two unexpected kisses from two different women.

Three gang members burst into the emergency room to kil a wounded rival and then hold several doctors and patient's hostage when police arrive before they can escape.