After the arrest of the boss Antonio Barone, the vice commissioner Andrea Lopez has a single objective: to prove and report the relations between Barone and his historical enemy, the corrupt director of the secret services Gerardo Facchini. The whole team works hard on the investigation, day and night without respite. Having obtained authorization from the commissioner Greco to meet Barone, Lopez places a bug in the protective apartment where the boss is staying. From the wiretaps our guys discover that Facchini and Barone will meet before a court hearing. There is little time to organize the operation, but for Lopez and the police officers of the team it is an unmissable opportunity, even if risky... Vitale has a small car accident with the father of a classmate of his daughter.

Lopez's death has left an unfillable void in the Spaccanapoli police station. While waiting for a new manager to arrive, command is temporarily entrusted to Ciccone who, from the start, feels burdened with too much responsibility. Sciacca and Battiston investigate the death of a businessman from the upper class of Naples. In the elegant shop where the man was killed, a pair of women's sunglasses are found: could it be a crime of passion? The victim's wife, outraged, rules out that her husband could have had a lover and firmly believes that it was a robbery. Yet the takings have not been touched. The two policemen have no choice but to find the owner of the mysterious glasses. A nativity scene shop is robbed. The owner, instead of going to the police, asks for help from the new neighborhood boss, Michele Malinconico. A passerby who witnessed the theft alerts the police at the Spaccanapoli police station.

Sciacca, Marciano and Coppola investigate the death of a young girl. The murderer, the victim's peer and friend, is found not far from the scene of the murder. At the police station, the police discover that the boy is incapable of understanding and willing: he will not end up in prison, but in a psychiatric hospital. Shortly afterward, a condominium fight breaks out in the victim's building. Sciacca suspects that the girl's parents are hiding something. His infallible instinct will prove him right once again. Malinconico is increasingly determined to conquer the city's drug market. The drug dealing areas of Spaccanapoli, however, are still in the hands of a small-time neighborhood boss. When one of these squares is razed to the ground, causing the death of a young boy who lived there with his mother and little sister, Vitale and the hawks become convinced that Malinconico organized the ambush.

Coppola and Marciano, on duty at the hospital, come across a young girl hospitalized for a wound to her hand. The doctor, however, is certain that the injury was caused by a cutting weapon. After listening to the teacher who accompanied the young woman to the emergency room, Coppola suspects that the girl is hiding something. Sciacca and Ciccone look for possible witnesses among the schoolmates. Could it be an episode of bullying? Vitale investigates the disappearance of his friend, the owner of the nightclub where Gabriele works. The inspector is convinced that Malinconico killed him after discovering that he was collaborating with the police. In the meantime, Battiston is pressured by the deputy commissioner Greco who demands concrete results. So, they decide to wiretap the cell phones of the boss's pushers and Matteo, more stubborn than ever, has an important intuition. Gabriele, unemployed again, accepts Malinconico's offer and starts working in his bar.

During a patrol, Coppola and his new driving partner, Persico, notice an abandoned car in front of a dilapidated building. Suspicious, the two police officers enter the building and find the body of a girl. The terrifying silence is broken by the rapid sound of footsteps. Federico tries to understand where they are coming from, but the killer, careful not to be seen, seriously wounds him and disappears into the darkness. The case involves the entire police station, shaken by the critical condition of the young officer. After the large cocaine seizure, the drug dealing squares of Spaccanapoli are empty. Our guys suspect that Malinconico is reorganizing, but they have no hold on anything to hold on to in order to restart the investigation. Gabriele, infiltrated in the Malinconico clan and Vitale's informant, suggests keeping an eye on a young drug dealer. Thanks to the valuable information, the inspector makes an important discovery.

The body of a Nigerian woman, who died at the airport shortly after arriving in Italy, is stolen from the morgue. Among the victim's personal effects, Battiston, Ciccone and Sciacca find a letter written by her daughter, who had been in Italy for some time and ended up in prostitution. What is behind the theft of the body? Will our heroes be able to save the girl? In order to continue following the investigation on Malinconico, Vitale reveals to Battiston and the anti-drug director Lamberti that Gabriele Coppola is his infiltrator in the boss's clan. Pretending to have always known and to support the chief inspector of the hawks, Battiston convinces Lamberti of the idea of ​​a collaboration. Meanwhile, an interview with a prostitute, rescued by Gabriele, threatens to blow his cover. When the boy doesn't show up for an appointment with Vitale, the suspicion that Malinconico has discovered everything becomes more and more certain. Bianca is worried about the custody of her son Giulio.

Marciano and Coppola, back together with the patrol cars, come across a Sinhalese man who is running away with his wife and son, completely covered by a sheet, from the building where he lives. When asked about the suspicious escape, the man replies that he wants to protect his child from the harsh spectacle of the drug addicts who gather every day in the courtyard. Once inside the building, the two officers find a crack house. Could it be the work of Malinconico? The investigation into the crack house soon passes to Vitale and his team of hawks. The inspector finds himself having to manage the disturbances in the neighborhood: the exasperated residents of Spaccanapoli take out their anger on the Sinhalese who live in the building, guilty of having attracted the police. During the riot, Sciacca notices a man whose face reminds him of something. Gabriele Coppola, under pressure, wants to leave his job as an infiltrator in the Malinconico clan, but he can't.

The men of the Spaccanapoli police station are looking for damning evidence to definitively frame the boss Malinconico. Gabriele discovers that a large shipment of cocaine is about to arrive in Naples. Vitale, having heard the news, leaves the cover apartment and moves to the police station. The inspector works day and night with his team of hawks to discover the method through which Malinconico manages to elude customs controls at the port. Lamberti devises a plan. A story of rivalry, envy and deceit in the world of youth sports for Sciacca and Ciccone who investigate the death of the coach of a junior soccer team. From the first interrogations it emerges that the victim had a relationship with the mother of one of the young soccer players. The betrayed father, having discovered his wife's relationship with the coach, had threatened the latter on several occasions. Could it be just a crime of passion? Vicky can't stay away from Gabriele.

Lamberti and Vitale work day and night to find damning evidence that will frame Malinconico once and for all. The two investigate the customs agents corrupted by the boss in search of news about the arrival in Naples of a large shipment of cocaine. One of them has a son who ended up in a wheelchair following the attack on a judge. Vitale suspects that something is hidden behind the tragic episode. Malinconico keeps Gabriele hidden to protect him from possible retaliation by the Colombians who hold him responsible for the arrest of their boss Castillo. Unable to track him down, Desirée becomes convinced that Gabriele is with Vicky and goes to look for her at the police station. Having located the policewoman's desk and distracted the agents present, the girl makes a shocking discovery. After committing a mugging in front of our people, an Afghan becomes ill and faints. Ciccone and Marciano rush him to the hospital.